^ Osawa Y, Azuma K, Tabata S, Katsukawa F, Ishida H, Oguma Y, Kawai T, Itoh H, Okuda S, Matsumoto H (2014). "Effects of 16-week high-intensity interval training using upper and lower body ergometers on aerobic fitness and morphological changes in healthy men: a preliminary study". Open Access Journal of Sports Medicine. 5: 257–65. doi:10.2147/OAJSM.S68932. PMC 4226445. PMID 25395872.
Physical activity boosts the immune system. This is dependent on the concentration of endogenous factors (such as sex hormones, metabolic hormones and growth hormones), body temperature, blood flow, hydration status and body position. Physical activity has shown to increase the levels of natural killer (NK) cells, NK T cells, macrophages, neutrophils and eosinophils, complements, cytokines, antibodies and T cytotoxic cells. However, the mechanism linking physical activity to immune system is not fully understood.
New (July 2011) guidelines in the United Kingdom include the following points: The intensity at which we exercise is key, and light activity such as strolling and housework is unlikely to have much positive impact on the health of most people. For aerobic exercise to be beneficial it must raise your heartbeat and make you sweat. The more exercise you do, the better. Everyone should do a minimum of 150 minutes a week of moderate-intensity aerobic exercise but that really is the minimum for health benefits. If you can go beyond 150 minutes, you’ll gain even more health benefits. Sedentary time (time spent sitting down to watch TV, use a computer, read or listen to music) is bad for your health, even for those who are achieving 150 minutes of exercise a week. These guidelines, are now much more in line with those used in the US, also include recommendations for muscle-building and bone strengthening activities such as lifting weights and yoga.